Drug-Excipient compatibility

Select dosage form components that are compatible with the drug. Let us help you design, conduct, and interpret the compatibility studies to help accelerate formulation development activities and prevent or minimise surprises in drug development.

By conducting the compatibility studies, you can find out if an excipient:

  • Induce or inhibit chemical degradation?
  • Promote or delay the physical form transition?
  • Eliminate or increase the disproportionation risk of a salt?
  • Induce or inhibit the deliquescence of the drug substance or excipient? 

Let’s Help!

Dr. Fozia Shah, Project Manager


Chadha R,  Bhandari S (2014) Drug–excipient compatibility screening—Role of thermoanalytical and spectroscopic techniques, J Pharm Biomed 87:82-97

Gallo LC, Gonzalez Vidal NL, Ferreira FF et al. (2021) Sulbactam pivoxil powder attributes and compatibility study with excipients. Futur J Pharm Sci 7, 26 

Soares-Sobrinho JL, de La Roca Soares MF, Lopes PQ, Correia LP, de Souza FS, Macêdo RO, Rolim-Neto PJ (2010) A pre-formulation study of a new medicine for Chagas disease treatment: physicochemical characterisation, thermal stability, and compatibility of benznidazole. AAPS PharmSciTech 11(3):1391-1396.

Qiu, Y. (2009). In Developing solid oral dosage forms: Pharmaceutical theory and practice, Chapter 6. Excipient Compatibility and Functionality (pp. 151-179). Academic Press. 

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