Solid-state Analysis

Are you looking to

  • Select a stable, robust, and reproducible drug product?
  • Mitigate development risks?
  • Set adequate acceptance limits for quality specifications?

Select the stable form as soon as possible and study all-solid-state properties.

Monitor properties of each batch. 

For particle/powder analysis, we can offer:

  • Examination of particles sizes
  • Particle morphology by optical and scanning electron microscopy
  • Specific and outer surface area
  • Porosity
  • Hygroscopicity
  • Crystallinity, polymorphic purity 
  • Thermal properties: melting point, glass transition, heat capacity, sublimation etc.
  • Dissolution rate
  • Stability
  • Density, including bulk and tapped density
  • Single-crystal structure determination (non-GMP)
  • IR spectra for identification and imaging
  • Raman spectroscopy
  • Other – please ask 

Consult our Experts

Dr. Wenbo Wang
QC Chemist

Dr. Anna Shevchenko
Principal Scientist

Literature

BYRN, S. R., PFEIFFER, R. R., & STOWELL, J. G. (1999). Solid-state chemistry of drugs. West Lafayette, Ind, SSCI, Inc. 

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