Dynamic Light Scattering

Measure particle size at the nanoscale​

Dynamic Light Scattering (DLS)

Dynamic Light Scattering (DLS) is a valuable technique for measuring the size and distribution of nanoparticles and colloidal systems in pharmaceutical formulations.

It is especially useful for characterizing small particles in solutions and dispersions, providing crucial insights into product stability and performance.

At Particle Analytical, DLS services are offered using the Malvern Zetasizer Ultra and Malvern Zetasizer Ultra/PRO, which also feature zeta potential measurement.

How Particle Analytical can assist with DLS

  • Nanoparticle Size Distribution

    Measures particle size distribution in nanoscale materials (0.5nm-1µm), essential for developing nanoparticle-based drug delivery systems

  • Zeta Potential Measurement

    Determines particle surface charge, which helps understand colloidal stability and predict or control aggregation.

  • Stability Analysis

    Monitors the stability of colloidal dispersions, emulsions, and suspensions, ensuring consistent performance over the product’s shelf life.

  • Formulation Development

    Ensures particles remain within the desired size range, optimizing drug delivery and absorption.

  • Protein and Biomolecule Characterization

    Analyzes proteins and biomolecules in solution, assessing stability of secondary structure and factors like aggregation and purity.

    Liposome and Micelle Characterization

    Provides insights into the size and distribution of liposomes and micelles, which are key to targeted drug delivery systems.

  • Quality Control Support

    Ensures particle size and zeta potential remain consistent across batches, supporting high quality of products.