Intrinsic Dissolution
Precision in drug solubility analysis
Intrinsic Dissolution
Intrinsic dissolution helps studying the dissolution rate of active pharmaceutical ingredients (APIs) under controlled conditions. Using this method, it is possible to mask effect of particle size and only register the effect of intrinsic properties of different solid-state forms on the dissolution rate.
At Particle Analytical, we conduct intrinsic dissolution testing using the Vankel Dissolution system combined with the Varian Cary 50 UV-VIS Spectrophotometer for detection. This equipment offers valuable data for early-stage formulation development, and solid-state form selection.
How Particle Analytical can help with Intrinsic Dissolution
Intrinsic Solubility Measurement
Provides accurate data on the dissolution rate of APIs, essential for understanding differences in various solid-state forms of APIs.
Formulation Development
Enable selection of the most optimal solid-state form to be used in formulation
Aid solid-state form selection
Used as a tool to select the optimal salt, cocrystal, solvate or polymorphic form for pharmaceutical product development.
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By choosing Particle Analytical, you get a strong and specialized partner, with a wide range of analysis, scalable and flexible services, and strong accreditations.