Workshop Copenhagen Nov. 1. 2012

Workshop:  Particle Characterization – Why should I care?

  • November 1, 2012. 13.00-16.30, Hotel Bella Sky, Copenhagen

We are happy to invite you to this 1. Workshop held by Particle Analytical about the importance of physical characterization of particles.  Participation is free (but a fee of DKK 500 will be charged to cover the expenses in case of no-show.) Sign up at Please read the abstracts below.


  • 13.00-13.45: Welcome and light lunch. Presentation of Particle Analytical
  • 13.45-14.15: Physical characterization of particles: Why should I care?
  • 14.15-14.30: Coffee break
  • 14.30-15.00: Polymorph screening – which approach to use?
  • 15.00-15.30: Examples of pitfalls in determination of particle size and shape
  • 15.00-15.30: Questions, discussion
  • 15.30-16.30: Networking over a cocktail at Sky Bar with a view of Copenhagen,

Note: If you should want a similar workshop closer to your home, do not hesitate to contact us. We look forward to seeing you. Best regards

Søren Lund Kristensen/on behalf of all employees at Particle Analytical

  •  Address: Bella Sky Comwell,Center Boulevard5, 2300 Kbh. S. Metro: Bella Center


  • Solid state characterization is essential in order to understand and control a compound during development. Lack of control of the particles increases the risk of sudden transformations, leading to changes in the stability and properties of the compound. Such changes might have large consequences for the behavior of the compound during manufacturing and -ultimately- in vivo. I.e. the potential risk, if these analyses are not performed, is that the analytical program and the clinical studies have to be repeated, which of course is quite costly.
  • Most solid materials are capable of forming different crystalline structures, known as polymorphic forms. These polymorphic forms have different physicochemical properties that might have significant impact on the intended use of the material. It is of immense importance to determine the crystal form in order to minimize the risk of transformation into other forms during development or, even worse, after introduction to the market. We present a rational approach to meet this risk.
  • Particle size and shape are often critical parameters in the manufacture of many products. The goal of all particle-sizing techniques is to provide a single number that is indicative of the particle size. However, particles are three-dimensional objects for which at least three parameters (length, breadth and height) are required in order to provide a complete description.  Thus, measurement of particle size is not an exact technique and a “true” value does not exist. A range of analytical techniques is available; these all have their strengths and weaknesses. Some examples of pitfalls in particle analysis will be given.