Workshop: Powder Analysis – Copenhagen Feb. 20. 2013

Workshop:  Powder Analysis – Why should I care?

  • February 20. 2013. 13.00-16.30, Hotel Bella Sky, Copenhagen

We are happy to invite you to this 2. Workshop held by Particle Analytical about the importance of analysis of powder/particles. The primary focus is on pharmaceutical products.  Participation is free (but a fee of DKK 500 will be charged to cover the expenses in case of no-show.) Sign up at Please read the abstracts below.


  • 13.00-13.45: Welcome and light lunch. Presentation of Particle Analytical
  • 13.45-14.15: Powder/particle analysis: Why should I care?
  • 14.15-14.30: Coffee break
  • 14.30-15.00: Polymorph screening – searching for new crystalline structures – which approach to use?
  • 15.00-15.30: Examples of pitfalls in determination of particle size and shape
  • 15.00-15.30: Questions, discussion
  • 15.30-16.30: Networking over a cocktail at Sky Bar with a view of Copenhagen,

Note: If you should want a similar workshop closer to your home, do not hesitate to contact us. We look forward to seeing you. Best regards

Søren Lund Kristensen/on behalf of all employees at Particle Analytical

  •  Address: Bella Sky Comwell,Center Boulevard5, 2300 Kbh. S. Metro: Bella Center


  • Particle analysis is essential in order to understand and control a compound during development. This analysis  includes information about size, shape and crystalline structure. Lack of control of the particles increases the risk of sudden transformations, leading to changes in the stability and properties of the compound. Such changes might have large consequences for the behavior of the compound during manufacturing and -ultimately- in vivo. I.e. the potential risk, if these analyses are not performed, is that the analytical program and the clinical studies have to be repeated, which of course is quite costly.
  • Most solid materials are capable of forming different crystalline structures, known as polymorphic forms. These polymorphic forms have different physicochemical properties that might have significant impact on the intended use of the material. It is of immense importance to determine the crystalline structure in order to minimize the risk of transformation into other structures during development or, even worse, after introduction to the market. We present a rational approach to meet this risk. Further, methods for determination of the “degree of crystallinity” will be presented,
  • Particle size and shape are often critical parameters in the manufacture of many products. The goal of all particle-sizing techniques is to provide a single number that is indicative of the particle size. However, particles are three-dimensional objects for which at least three parameters (length, breadth and height) are required in order to provide a complete description.  Thus, measurement of particle size is not an exact technique and a “true” value does not exist. A range of analytical techniques is available; these all have their strengths and weaknesses. Some examples of pitfalls in particle analysis will be given.