Solid form studies
Exploring solid form studies in pharmaceuticals
Why Solid State Screening?
Solid state form screening is a vital process in the pharmaceutical industry. It is crucial for identifying the most stable and bioavailable forms of drug compounds.
Our expert team uses advanced analytical techniques to conduct comprehensive screenings; including: salt, co-crystal, amorphous solid dispersion and polymorph screenings.
Amorphous Solid Dispersion Screening
Solid-state form screening, including salts, cocrystals, and amorphous solid dispersions, is particularly important as it helps to enhance the solubility and dissolution rates of poorly soluble drugs.
Identifying optimal solid state forms
By identifying the optimal solid-state forms, pharmaceutical companies can improve drug performance, stability, and manufacturability, ultimately leading to better patient outcomes and more efficient production processes.
Polymorph screening – the right polymorph
Building on the foundation of solid-state screening, polymorph screening is another essential component. Polymorph screening focuses on identifying different crystalline forms – polymorphs – of a drug compound. The polymorphs possess each unique physical and chemical properties such as solubility, stability, and bioavailability.
How to find the right polymorph?
Selecting the most suitable polymorph is crucial for ensuring the drug’s efficacy and stability throughout its shelf life. Understanding the polymorphic landscape allows for informed decisions on the best form for development and commercialization.
Securing Competitive Advantage with IP Rights
With the identification of optimal solid state forms and polymorphs, the next step is securing intellectual property (IP) rights. Protecting these forms through robust IP rights provides significant competitive advantages.
Tailored approach to solid state form screening
We provide detailed reports and actionable insights for optimizing your formulations and assist in securing IP rights to protect your innovations.
Tendency Evaluation
A preliminary assessment to identify the potential for polymorphism.
Small Scale Evaluation
Focused screening with a limited number of experiments to identify polymorphic forms.
Medium Scale Screening
An extensive study involving a broader range of conditions and experiments to uncover additional polymorphs.
Comprehensive Screening Study
An in-depth investigation covering extensive experimental conditions to provide a complete polymorphic profile.
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