Particle characterization
Leading particle characterization services
Risk mitigation – comprehensive product characterization
Understanding the detailed characteristics of your product’s particles is crucial in pharmaceutical development. Whether you’re optimizing a formulation, ensuring regulatory compliance or enhancing product performance – solid-state characterization offers the necessary insights to guide informed decision-making.
By analyzing properties such as particle size, morphology or polymorphism, you can achieve a comprehensive understanding of your product’s behavior and quality. Particle characterization provides detailed analysis of the physical properties of particles.
These properties can significantly influence the performance, stability and efficacy of pharmaceutical products. Understanding these properties is essential for optimizing formulations, ensuring product consistency – complying with regulatory requirements.
Key Properties Measured in Solid-State Characterization
Our particle characterization services provide insights into key particle properties, ensuring optimal formulation and manufacturing processes.
Particle Size Distribution (PSD)
Critical for ensuring uniformity in dosage and influencing the dissolution rate of the drug.
Morphology
The shape and surface features of particles, which can affect flowability, compaction, and overall processing behavior.
Polymorphism
The study of different crystalline forms of a substance, which can impact the drug’s solubility, stability, and bioavailability.
Shape
Particle shape influences flow characteristics and packing density, impacting the manufacturing process and final product quality.
Surface Area
Larger surface areas can enhance dissolution rates and affect the drug’s absorption in the body.
Porosity
Affects how a drug dissolves and releases its active ingredient, impacting its performance and stability.
Density
Both bulk and tapped density are important for understanding the powder’s behavior during processing and its final dosage form.
Moisture Content
Crucial for stability, as excessive moisture can lead to degradation or changes in the material’s properties.
Flowability
Ensures smooth processing in manufacturing, reducing the risk of blockages and ensuring uniformity in drug production.
Thermal Properties
Analyzed through techniques such as DSC and TGA, thermal properties provide insights into a material’s stability and suitability for various manufacturing processes.
Solubility and Dissolution Rate
Key factors that determine the drug’s bioavailability, influencing how quickly and efficiently the drug is absorbed in the body.
Understanding your product
Understanding the detailed characteristics of your product’s particles is crucial in the pharmaceutical industry. Whether you’re optimizing a formulation, ensuring regulatory compliance, or seeking to enhance product performance, solid-state characterization provides the insights needed to make informed decisions.
By analyzing properties such as particle size, morphology, polymorphism, and more, you can gain a comprehensive understanding of your product’s behavior and quality.
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How we can help
Learn more about How we can help you addressing problems in your development or manufacturing process, by applying our strong technical and analytical skills.
Knowledge Hub
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Why choose us
By choosing Particle Analytical, you get a strong and specialized partner, with a wide range of analysis, scalable and flexible services, and strong accreditations.